Now all webform file elements have an option to automatically rename uploaded files. You can use tokens to specify the destination filename.
The option is called "Rename files". It can take values like: cv_[webform_submission:values:your_name] - this example assumes you have an element named your_name within the same webform. So it would automatically rename the file to cv_[name-of-the-applicant].[extension-of-original-file]. Do note that you should not provide extension in the "Rename files" text field - the extension is taken from the uploaded file.
If you wonder what happens when you allow to upload multiple files, they are simply going to be named with _0, _1 on so on suffix (pretty common Drupal practise). So multiple files from our CV example above would end up being: cv_joe.pdf, cv_joe_0.pdf on so forth.
For further information refer to the webform issue #2941286: Rename file uploads for v8.x