Can you integrate with Rules?

The module is nice, but the problem I see is the configuration for a content author user not being friendly.

Lets say I have 20 content types. A user of role "Supplier" can insert his business choosing between one of them, and if he becomes a "Pro Supplier", he can then administer comments on his nodes.

There is a single user role which can create many content types, but will actually use only 1 of them (and maybe other two of general type) and will administer comments only in his specific content type.
Of course I cannot know which content type he will choose, cannot change permissions with Rules, and creating 20 user roles is unfeasible.

So, the problem is that he will have to set the "Skip comment approval" configuration on all content types, or choose from a very long and ugly list, which I cannot hide programmaticaly.

It would be VERY helpful if we could set the "Skip comment approval" configuration on the user profile with rules.