I did a search on panels and didn't see an issue for this so I apologize if it's a dupe...
The panels integration for viewing fields/fieldgroups is great but now I want it on the editing end, too. :) Panels has a great potential for organizing the node edit form. Some of what's needed may be on the panels end because it will need to have something for the per node type display like the node view currently has. But part of it is being able to select individual CCK fields/fieldgroups to add to the panel.
Unfortunately, this part is something I have no idea how to do so all I can do is put in a FR for it.