Drupella File Manager is a commercial module ($40) for file management that supports drag-and-drop between folders. You can upload multiple files by dragging them into the open folders from your local file system. Files can be edited from within the file manager and it updates the file_managed table within the database accordingly. This module integrates well with the CKEditor module and the FileField Sources module. Permissions can be configured to allow/disallow access to the public and private file systems and a file manager can be attached to a user's account page.
Go to Drupella's website for a demo, installation instructions and to purchase a license.
There is also a free version that shares the same module codebase with the full version. It supports multiple uploads, file deletion and moving.