This might be more of an issue for a later version of Panopoly but I thought was maybe worth a discussion down the line.
When I saw that Custom Breadcrumbs was considering to be moving to Path Breadcrumbs (http://drupal.org/node/1823080#comment-6797992) a while back I thought I would give it a go and have to say am super impressed with it in terms of both architecture and ease of use (additionally great i18n). It basically can accomplish whatever panels breadcrumbs can but also work for any other part of a Drupal site given a proper context. Also since it leverages ctools is provides an experience that is very common to us Panels users (context, arguments, selection rules).
Thought I would just throw this out there :)