First, some numbers and basic facts. Also, a disclaimer: I'm a senior developer for Sugar Publishing.
TeamSugar is the community hub for Sugar Publishing's 8 content blogs, geared towards women. Across the whole network we reach about 21 million pageviews per month. The largest site of the bunch is PopSugar, which accounts for about 17 million of those pageviews. TeamSugar is the third, with about 1.1 million pageviews per month. Each pageview is served courtesy of Drupal.
Obviously the audience here is not so keen on the content (unless you really want to get the latest hullaballoo on Lindsay Lohan), but I'd be happy to answer what technical questions anyone might have since we're one of the larger Drupal installations out there. So, take a look, give us your feedback, and ask whatever questions you might have.