diff -u b/core/lib/Drupal/Core/Template/TwigEnvironment.php b/core/lib/Drupal/Core/Template/TwigEnvironment.php
--- b/core/lib/Drupal/Core/Template/TwigEnvironment.php
+++ b/core/lib/Drupal/Core/Template/TwigEnvironment.php
@@ -154,7 +154,7 @@
 
         // If autoreload is on, check that the template has not been
         // modified since the last compilation.
-        if ($this->isAutoReload() && !$this->isFresh($cache_filename, $name)) {
+        if ($this->isAutoReload() && !$this->isFresh($cache_filename, $name, $inline)) {
           $this->updateCompiledTemplate($cache_filename, $name, $inline);
         }
 
@@ -180,8 +180,8 @@
       }
     }
 
-      return $this->getLoader()->isFresh($name, $time);
-    }
+    return $this->getLoader($inline)->isFresh($name, $time, $inline);
+  }
 
   /**
    * Gets the PHP code storage object to use for the compiled Twig files.