diff -u b/core/modules/system/src/Form/ModulesUninstallForm.php b/core/modules/system/src/Form/ModulesUninstallForm.php
--- b/core/modules/system/src/Form/ModulesUninstallForm.php
+++ b/core/modules/system/src/Form/ModulesUninstallForm.php
@@ -143,11 +143,10 @@
         $form['uninstall'][$module->getName()]['#disabled'] = TRUE;
       }
       // All modules which depend on this one must be uninstalled first, before
-      // we can allow this module to be uninstalled. (The installation profile
-      // is excluded from this list.)
-      $dependents = array_diff_key($module->required_by, $profiles);
-      foreach (array_keys($dependents) as $dependent) {
-        if (drupal_get_installed_schema_version($dependent) != SCHEMA_UNINSTALLED) {
+      // we can allow this module to be uninstalled. (Installation profiles are
+      // excluded from this list.)
+      foreach (array_keys($module->required_by) as $dependent) {
+        if (!in_array($dependent, array_keys($profiles)) && drupal_get_installed_schema_version($dependent) != SCHEMA_UNINSTALLED) {
           $name = isset($modules[$dependent]->info['name']) ? $modules[$dependent]->info['name'] : $dependent;
           $form['modules'][$module->getName()]['#required_by'][] = $name;
           $form['uninstall'][$module->getName()]['#disabled'] = TRUE;