diff --git a/core/modules/outside_in/js/outside_in.es6.js b/core/modules/outside_in/js/outside_in.es6.js
index 76bb872749..c73e535035 100644
--- a/core/modules/outside_in/js/outside_in.es6.js
+++ b/core/modules/outside_in/js/outside_in.es6.js
@@ -9,6 +9,8 @@
   const itemsToToggleSelector = '[data-off-canvas-main-canvas], #toolbar-bar, [data-drupal-outsidein="editable"] a, [data-drupal-outsidein="editable"] button';
   const contextualItemsSelector = '[data-contextual-id] a, [data-contextual-id] button';
   const quickEditItemSelector = '[data-quickedit-entity-id]';
+  const excludedLinksSelector = '[data-outside-in-exclude] [data-outside-in-edit]';
+
 
   /**
    * Reacts to contextual links being added.
@@ -21,6 +23,10 @@
    * @listens event:drupalContextualLinkAdded
    */
   $(document).on('drupalContextualLinkAdded', (event, data) => {
+    // Remove contextual links that should be excluded.
+    // @see outside_in_block_view_alter().
+    $(excludedLinksSelector).remove();
+
     // Bind Ajax behaviors to all items showing the class.
     // @todo Fix contextual links to work with use-ajax links in
     //    https://www.drupal.org/node/2764931.
diff --git a/core/modules/outside_in/js/outside_in.js b/core/modules/outside_in/js/outside_in.js
index 95cf90e225..a27c40c7ce 100644
--- a/core/modules/outside_in/js/outside_in.js
+++ b/core/modules/outside_in/js/outside_in.js
@@ -11,8 +11,11 @@
   var itemsToToggleSelector = '[data-off-canvas-main-canvas], #toolbar-bar, [data-drupal-outsidein="editable"] a, [data-drupal-outsidein="editable"] button';
   var contextualItemsSelector = '[data-contextual-id] a, [data-contextual-id] button';
   var quickEditItemSelector = '[data-quickedit-entity-id]';
+  var excludedLinksSelector = '[data-outside-in-exclude] [data-outside-in-edit]';
 
   $(document).on('drupalContextualLinkAdded', function (event, data) {
+    $(excludedLinksSelector).remove();
+
     Drupal.attachBehaviors(data.$el[0]);
 
     data.$el.find(blockConfigureSelector).on('click.outsidein', function () {
diff --git a/core/modules/outside_in/outside_in.api.php b/core/modules/outside_in/outside_in.api.php
new file mode 100644
index 0000000000..e24ce8ce75
--- /dev/null
+++ b/core/modules/outside_in/outside_in.api.php
@@ -0,0 +1,18 @@
+<?php
+
+/**
+ * @file
+ * API Documentation provided by the Settings Tray module.
+ */
+
+/**
+ * @defgroup outside_in Settings Tray API
+ * @{
+ * Settings Tray API
+ *
+ * @section sec_excluding_blocks Excluding Blocks from Settings Tray
+ * To exclude a block from the Settings Tray "Quick Functionality" simply put a
+ * 'outside_in_exclude' key in the block plugin definition.
+ *
+ * @see \Drupal\outside_in_test\Plugin\Block\ExcludedTestBlock
+ */
diff --git a/core/modules/outside_in/outside_in.module b/core/modules/outside_in/outside_in.module
index 69517b9919..9445f0a3fc 100644
--- a/core/modules/outside_in/outside_in.module
+++ b/core/modules/outside_in/outside_in.module
@@ -64,6 +64,29 @@ function outside_in_block_view_alter(array &$build) {
   $build['#contextual_links']['outside_in'] = [
     'route_parameters' => [],
   ];
+
+  if (_outside_in_block_is_excluded($build['#plugin_id']) && isset($build['#contextual_links']['block'])) {
+    // If this block should not be editable set an attribute which will be used
+    // to remove the link on the client side.
+    // The individual links are not available here to remove.
+    // @see outside_in.js
+    $build['#attributes']['data-outside-in-exclude'] = TRUE;
+  }
+
+}
+
+/**
+ * Determines if block plugin should be excluded.
+ *
+ * @param string $plugin_id
+ *   The plugin id for the block.
+ *
+ * @return bool
+ *   True if the blocks with this plugin id should be excluded.
+ */
+function _outside_in_block_is_excluded($plugin_id) {
+  $definition = \Drupal::service('plugin.manager.block')->getDefinition($plugin_id);
+  return !empty($definition['outside_in_exclude']);
 }
 
 /**
@@ -101,7 +124,7 @@ function outside_in_entity_type_build(array &$entity_types) {
  */
 function outside_in_preprocess_block(&$variables) {
   // The main system block does not contain the block contextual links.
-  if ($variables['plugin_id'] !== 'system_main_block') {
+  if (!_outside_in_block_is_excluded($variables['plugin_id'])) {
     // Add class and attributes to all blocks to allow Javascript to target.
     $variables['attributes']['class'][] = 'outside-in-editable';
     $variables['attributes']['data-drupal-outsidein'] = 'editable';
@@ -145,12 +168,17 @@ function outside_in_block_alter(&$definitions) {
     $definitions['system_branding_block']['forms']['off_canvas'] = SystemBrandingOffCanvasForm::class;
   }
 
-  // Since menu blocks use derivatives, check the definition ID instead of
-  // relying on the plugin ID.
+  $exluded_blocks = ['page_title_block', 'system_main_block'];
   foreach ($definitions as &$definition) {
+    // Since menu blocks use derivatives, check the definition ID instead of
+    // relying on the plugin ID.
     if ($definition['id'] === 'system_menu_block') {
       $definition['forms']['off_canvas'] = SystemMenuOffCanvasForm::class;
     }
+
+    if (in_array($definition['id'], $exluded_blocks)) {
+      $definition['outside_in_exclude'] = TRUE;
+    }
   }
 }
 
diff --git a/core/modules/outside_in/tests/modules/outside_in_test/outside_in_test.info.yml b/core/modules/outside_in/tests/modules/outside_in_test/outside_in_test.info.yml
new file mode 100644
index 0000000000..590f559329
--- /dev/null
+++ b/core/modules/outside_in/tests/modules/outside_in_test/outside_in_test.info.yml
@@ -0,0 +1,9 @@
+name: 'Settings Tray Test'
+type: module
+description: 'Provides Settings Tray test functionality.'
+package: Testing
+version: VERSION
+core: 8.x
+dependencies:
+  - block
+  - outside_in
diff --git a/core/modules/outside_in/tests/modules/outside_in_test/src/Plugin/Block/ExcludedTestBlock.php b/core/modules/outside_in/tests/modules/outside_in_test/src/Plugin/Block/ExcludedTestBlock.php
new file mode 100644
index 0000000000..08ff81c70e
--- /dev/null
+++ b/core/modules/outside_in/tests/modules/outside_in_test/src/Plugin/Block/ExcludedTestBlock.php
@@ -0,0 +1,32 @@
+<?php
+
+namespace Drupal\outside_in_test\Plugin\Block;
+
+use Drupal\Core\Block\BlockBase;
+
+/**
+ * Provides a test block that is excluded from Settings Tray.
+ *
+ * @Block(
+ *   id = "outside_in_test_excluded",
+ *   admin_label = @Translation("Settings Tray Excluded Block"),
+ *   outside_in_exclude = true
+ * )
+ */
+class ExcludedTestBlock extends BlockBase {
+
+  /**
+   * {@inheritdoc}
+   */
+  public function defaultConfiguration() {
+    return ['label_display' => FALSE];
+  }
+
+  /**
+   * {@inheritdoc}
+   */
+  public function build() {
+    return ['#markup' => '<span>' . $this->t('Why did you exclude me?') . '</span>'];
+  }
+
+}
diff --git a/core/modules/outside_in/tests/src/FunctionalJavascript/OutsideInBlockFormTest.php b/core/modules/outside_in/tests/src/FunctionalJavascript/OutsideInBlockFormTest.php
index 313e12dc01..8b5b4d94d7 100644
--- a/core/modules/outside_in/tests/src/FunctionalJavascript/OutsideInBlockFormTest.php
+++ b/core/modules/outside_in/tests/src/FunctionalJavascript/OutsideInBlockFormTest.php
@@ -35,6 +35,7 @@ class OutsideInBlockFormTest extends OutsideInJavascriptTestBase {
     // Add test module to override CSS pointer-events properties because they
     // cause test failures.
     'outside_in_test_css',
+    'outside_in_test',
   ];
 
   /**
@@ -498,4 +499,33 @@ protected function isLabelInputVisible() {
     return $this->getSession()->getPage()->find('css', static::LABEL_INPUT_SELECTOR)->isVisible();
   }
 
+  /**
+   * Tests that title block does not have a outside_in contextual link.
+   */
+  public function testBlockExcluded() {
+    $web_assert = $this->assertSession();
+
+    $non_excluded_block = $this->placeBlock('system_powered_by_block');
+    $excluded_block_plugin_ids = ['page_title_block', 'system_main_block', 'outside_in_test_excluded'];
+    $block_selectors = [];
+    // Place blocks that should be excluded.
+    foreach ($excluded_block_plugin_ids as $excluded_block_plugin_id) {
+      // The block HTML 'id' attribute will be "block-[block_id]".
+      $block_selectors[] = $this->getBlockSelector($this->placeBlock($excluded_block_plugin_id));
+    }
+    $this->drupalGet('user');
+    // Assert that block has been marked as "editable" and contextual that
+    // should exist does.
+    $web_assert->elementExists('css', $this->getBlockSelector($non_excluded_block) . "[data-drupal-outsidein=\"editable\"]");
+    // Check each block that should be excluded.
+    foreach ($block_selectors as $block_selector) {
+      // Assert block itself exists.
+      $web_assert->elementExists('css', $block_selector);
+      // Assert that exclude block has not been marked as "editable".
+      $web_assert->elementNotExists('css', "{$block_selector}[data-drupal-outsidein=\"editable\"]");
+      // Assert that contextual that not should exist does not.
+      $web_assert->elementNotExists('css', "$block_selector [data-outside-in-edit]");
+    }
+  }
+
 }